AYU (An International Quarterly Journal of Research in Ayurveda)

PHARMACOLOGICAL STUDY
Year
: 2013  |  Volume : 34  |  Issue : 3  |  Page : 302--304

Anti‑inflammatory effect of Chandrashura (Lepidium sativum Linn.) an experimental study


Nita D Raval1, B Ravishankar2, BK Ashok3 
1 Lecturer, Department of Dravyaguna, Government Ayurvedic Collage, Junagadh, Gujarat, India
2 Director, SDM Research Centre for Ayurveda and Allied Sciences, Kuthpady, Udupi, India
3 Drug Discovery Team, Research and Development, The Himalaya Drug Company, Makali, Bangalore, Karnataka, India

Correspondence Address:
Nita D Raval
Patel Colony 2/2, Ashirvad Tenaments, Jamnagar, Gujarat
India

Lepidium sativum Linn. (Chandrashura) of Family Cruciferae (Brassicaceae) is being used by the people of Gujarat for treating inflammatory condition like arthritis. To evaluate its anti-inflammatory activity, Charles Foster albino rats were selected and experiments were carried out in three groups, therapeutic dose group, twice of therapeutic dose group and control group. In Carrageenan-induced paw oedema, the test drug produced moderate anti-inflammatory activity; however, the effect did not show statistically significant activity due to variation in the data of the control group. In formaldehyde-induced paw oedema in rats, the test drug produced moderate to significant suppression. This indicates that Chandrashura has a strong inhibitory effect on proliferation of fibroblasts and also probably has connective tissue modulation effect.


How to cite this article:
Raval ND, Ravishankar B, Ashok B K. Anti‑inflammatory effect of Chandrashura (Lepidium sativum Linn.) an experimental study.AYU 2013;34:302-304


How to cite this URL:
Raval ND, Ravishankar B, Ashok B K. Anti‑inflammatory effect of Chandrashura (Lepidium sativum Linn.) an experimental study. AYU [serial online] 2013 [cited 2020 Oct 24 ];34:302-304
Available from: https://www.ayujournal.org/article.asp?issn=0974-8520;year=2013;volume=34;issue=3;spage=302;epage=304;aulast=Raval;type=0