AYU (An International Quarterly Journal of Research in Ayurveda)

PHARMACOLOGICAL STUDY
Year
: 2013  |  Volume : 34  |  Issue : 1  |  Page : 109--112

In vitro α -amylase and α-glucosidase inhibitory potential of Trigonella foenum-graecum leaves extract


Aditya Ganeshpurkar1, Varsha Diwedi2, Yash Bhardwaj2 
1 Assistant Professor, Drug Discovery Laboratory, Department of Pharmacology, Shri Ram Institute of Technology-Pharmacy, Jabalpur, Madhya Pradesh, India
2 B.Pharm. Scholar, Drug Discovery Laboratory, Department of Pharmacology, Shri Ram Institute of Technology-Pharmacy, Jabalpur, Madhya Pradesh, India

Correspondence Address:
Aditya Ganeshpurkar
Drug Discovery Laboratory, Shri Ram Institute of Technology-Pharmacy, Jabalpur - 482 002, Madhya Pradesh
India

Trigonella foenum-graecum is one of the widely used herbs in food and medicine. The seeds of the plants are investigated for antidiabetic potential; however, no efforts have been done to explore the potential of leaves to modify carbohydrate metabolizing enzymes viz. α-amylase and α-glucosidase. The present work was designed to investigate the inhibitory potential of ethyl acetate and water extract of T. foenum-graecum on enzymes α-amylase and α-glucosidase. Different concentrations of extracts were used to study inhibition of enzymatic activity of α-amylase and α-glucosidase. A dose dependent inhibitory effect on enzymes was observed. The current study, for the first time, revealed α-amylase and α-glucosidase inhibitory potential of T. foenum-graecum and the study could be helpful to isolate and characterize compounds responsible for it.


How to cite this article:
Ganeshpurkar A, Diwedi V, Bhardwaj Y. In vitro α -amylase and α-glucosidase inhibitory potential of Trigonella foenum-graecum leaves extract.AYU 2013;34:109-112


How to cite this URL:
Ganeshpurkar A, Diwedi V, Bhardwaj Y. In vitro α -amylase and α-glucosidase inhibitory potential of Trigonella foenum-graecum leaves extract. AYU [serial online] 2013 [cited 2021 Jan 25 ];34:109-112
Available from: https://www.ayujournal.org/article.asp?issn=0974-8520;year=2013;volume=34;issue=1;spage=109;epage=112;aulast=Ganeshpurkar;type=0