AYU (An International Quarterly Journal of Research in Ayurveda)

SHORT COMMUNICATION
Year
: 2012  |  Volume : 33  |  Issue : 2  |  Page : 314--316

Anti-ulcer activity of Lucer against experimentally induced gastric ulcers in rats


Jigna S Shah1, Jetun R Patel2 
1 Professor, Department of Pharmacology, Shri Sarvajanik Pharmacy College, Mehsana, Gujarat, India
2 Clinical Research Associate, Parexel International, United Kingdom

Correspondence Address:
Jigna S Shah
Department of Pharmacology, Shri Sarvajanik Pharmacy College, Mehsana-384 001, Gujarat
India

The present study is designed to explore the mechanism of action of herbal formulation Lucer against experimentally induced gastric ulcers. The aqueous extract (120 and 180 mg/kg) of Lucer was tested against aspirin and ethanol-induced gastric ulcer model in rats. The drug has been found to be very effective in inhibiting gastric ulceration. This is evident from reduction in ulcer index parameters. Besides, significant reduction in acid secretory parameters such as total acidity, total acid output and volume of gastric secretion were also observed. It is concluded from this study that the drug possesses anti-ulcer activity in both the models. The anti-ulcer activity of the drug can be attributed to inhibition of acid secretary parameters and strengthening of gastric mucosal barrier.


How to cite this article:
Shah JS, Patel JR. Anti-ulcer activity of Lucer against experimentally induced gastric ulcers in rats.AYU 2012;33:314-316


How to cite this URL:
Shah JS, Patel JR. Anti-ulcer activity of Lucer against experimentally induced gastric ulcers in rats. AYU [serial online] 2012 [cited 2021 Dec 2 ];33:314-316
Available from: https://www.ayujournal.org/article.asp?issn=0974-8520;year=2012;volume=33;issue=2;spage=314;epage=316;aulast=Shah;type=0