AYU (An International Quarterly Journal of Research in Ayurveda)

RESEARCH ARTICLE
Year
: 2009  |  Volume : 30  |  Issue : 2  |  Page : 175--180

Toxicological evaluation of Cynoglossum glochidiatum Wall. ex. Benth (Tejaraj), a folklore aphrodisiac medicinal plant


RN Acharya1, VJ Shukla2, KP Skandhan3, PP Sharma4, B Ravishankar5 
1 Reader, Dept. of Dravyaguna, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India
2 Head-Pharmaceutical Chemistry, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India
3 Ex. Professor of Physiology, MP Shah Medical College, Jamnagar, India
4 Head-Dept. of Dravyaguna, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India
5 Head-Pharmacology Laboratory, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India

Correspondence Address:
R N Acharya
Reader, Dept. of Dravyaguna, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar
India

Roots of Cynoglossum glochidiatum Wall.ex. Benth of Family Boraginaceae identified as source plant of Tejaraj is being used by tribal people of Orissa (Kandha) for treating male sexual dysfunctions and infertility. A pharmacological study was carried out to evaluate toxic effect (if any) of the root of C. glochidiatum in two phases i.e. short term(15 days) in high dose(2500 mg./kg.) and long term (60 days) in human equivalent dose (500 mg./kg.) in albino rats. The parameters studied were ponderal, haematological, biochemical and histopathological changes. The test drug did not produce any mortality or significant toxic effect on different organs except for producing increase in blood urea level and moderate fatty degenerative changes in liver.


How to cite this article:
Acharya R N, Shukla V J, Skandhan K P, Sharma P P, Ravishankar B. Toxicological evaluation of Cynoglossum glochidiatum Wall. ex. Benth (Tejaraj), a folklore aphrodisiac medicinal plant.AYU 2009;30:175-180


How to cite this URL:
Acharya R N, Shukla V J, Skandhan K P, Sharma P P, Ravishankar B. Toxicological evaluation of Cynoglossum glochidiatum Wall. ex. Benth (Tejaraj), a folklore aphrodisiac medicinal plant. AYU [serial online] 2009 [cited 2021 Sep 22 ];30:175-180
Available from: https://www.ayujournal.org/article.asp?issn=0974-8520;year=2009;volume=30;issue=2;spage=175;epage=180;aulast=Acharya;type=0