Login   |  Users Online: 273 Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Search Article 
  
Advanced search 
   Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | Subscribe | Contacts
PHARMACOLOGICAL STUDY
Year : 2013  |  Volume : 34  |  Issue : 2  |  Page : 215-219

Effect of Drakshavaleha in cyclophosphamide induced weight loss and reduction in crown-rump length in developing mice embryo


1 Associate Professor Department of Sharira Rachana, National Institute of Ayurveda, Jaipur, India
2 Prof of Anatomy and Ex. Director, Institute of Medical Sciences, BHU, Varanasi, India
3 Associate Prof. Department of Rasashastra, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

Correspondence Address:
Sunil Kumar
Associate Professor, Department of Sharira Rachana, National Institute of Ayurveda, Jaipur - 302 002, Rajasthan
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-8520.119686

Rights and Permissions

Being an anti-mitotic and apoptosis inducing agent, Cyclophosphamide (CP) causes stunting in size and loss of body weight of the pups on intra-peritoneal injection (10 mg/kg) to pregnant mice on day 11 of gestation. Loss of body weight due to CP administration could be minimized by feeding Drakshavaleha (16 g/kg) orally to pregnant mice from day "0" to day "18" of their gestation. Recovery observed in terms of body weight of the pups was statistically significant (P < 0.001) in Drakshavaleha treated pups. Drakshavaleha also recovered the crown-rump length of the pups occurred due to CP administration. Growth retardation with decreased fetal weight was observed in all CP treated pups when compared with the controls.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2419    
    Printed45    
    Emailed0    
    PDF Downloaded459    
    Comments [Add]    
    Cited by others 1    

Recommend this journal