Immunomodulatory activity of Vachadhatryadi Avaleha in albino rats

S Rajagopala; BK Ashok; B Ravishankar

doi:10.4103/0974-8520.92546

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PHARMACOLOGICAL RESEARCH

Year : 2011 | Volume : 32 | Issue : 2 | Page : 275-278

Immunomodulatory activity of Vachadhatryadi Avaleha in albino rats

S Rajagopala¹, BK Ashok², B Ravishankar³
¹ Assistant Professor, Department of Kaumarabhritya, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India
² Research Assistant, Pharmacology Laboratory, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India
³ Ex.Head, Pharmacology Laboratory, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India

Correspondence Address:
S Rajagopala
Department of Kaumarabhritya, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar - 361 008, Gujarat
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/0974-8520.92546

The present study is carried out to evaluate the immuno-modulatory activity of Vacha Dhatryadi Avaleha in albino rats. Vacha Dhatryadi Avaleha was prepared by classical method and evaluated for humoral antibody formation and cell-medicated immunity in established experimental models. Test formulation was administered at the dose of 900 mg/kg and parameters like hemagglutination titer, ponderal changes, histopathology of immunological organs and immunological paw edema were recorded. Vacha Dhatryadi Avaleha significantly enhanced antibody formation and moderately suppressed the immunological edema. The present study concludes that Vachadhatryadi Avaleha has immunopotentiating activity.

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