An approach of Ashwagandha + Guggulu in Atheromatous CHD associated with Obesity
Raakhee Mehra1, Mahadeo Prasad2, GS Lavekar3
1 Asstt. Director (Ay.), Central Research Institute for Ayurveda, CCRAS, Dept. of AYUSH, Ministry of Health & F.W., Govt of India, New Delhi, India
2 Asstt. Director Incharge, Central Research Institute for Ayurveda, CCRAS, Dept. of AYUSH, Ministry of Health & F.W., Govt of India, New Delhi, India
3 Director – CCRAS, Central Research Institute for Ayurveda, CCRAS, Dept. of AYUSH, Ministry of Health & F.W., Govt of India, New Delhi, India
Asstt. Director (Ay.), Central Research Institute for Ayurveda, CCRAS, Dept. of AYUSH, Ministry of Health & F.W., Govt of India, New Delhi
Source of Support: None, Conflict of Interest: None
The Coronary Artery Disease or Coronary Heart Disease is the single biggest killer (60%) and the most common cause of maximum morbidity, ironically. Infact this is a disease whose control is most in our hands and it is most life style dependent. In accordance with the latest reports more than 13.7% of the adult population is suffering from coronary heart disease in India, and this figure is constantly on the rise year after year. The main cause of the disease is obesity in terms of enhanced circumference, deposition of cholesterol and fat in the inner smooth lining of the coronary arteries supplying blood to the heart resulting in their blockages and obstruction to blood flow through them. Atheromatous plaque is formed which constricts the flow of blood, oxygen, and nutrients to the heart muscles. With significant blockages, about 60% to 70% of the vessel wall and exertion the increased demand of blood by the heart is not met. More than 100 number of risk factors responsible for the development of CHD are documented. Williams in 1981 identified 246 risk factors that directly or indirectly lead to the development and onset of heart disease. The excess risk is closely related to the plasma concentration of LDL cholesterol and is inversely related to the plasma concentration of LDL cholesterol and is inversely related to the plasma HDL Cholesterol concentration. There is also a weak correlation between plasma triglyceride concentration and the incidence of coronary artery disease. Moreover, numerous clinical trials have shown that lowering high cholesterol concentrations by diet or drugs can reduce the risk of cardiac events. Moreover, many allopathic antihypertensive drugs have been shown to reduce coronary mortality but by less than might have been anticipated, possibly because many of these agents have potentially adverse effects on lipid and glucose metabolism. Ayurvediya care from both the preventive and therapeutic ways like primary protection in terms of Swasthya Vritta with Aushadha along with Pathyapathya and Ashwagandha+Guggulu provide tremendous results with secondary cardio protection by their anti hyperlipidamic, antiatherosclerotic, antihypertensive actions. All the patients already on prescribed allopathic medicine and cardiac diet were taken. An attempt to evaluate the efficacy of ayurvediya Ashwagandha+Shuddha guggulu in 500mg twice daily in 20 patients of atheromatous coronary hypertensive heart patients associated with obesity is made at Clinical Research Unit, Safadarjang Hospital New Delhi during 2007.