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RESEARCH ARTICLE
Year : 2006  |  Volume : 27  |  Issue : 1  |  Page : 1-8

A pharmaceutical standardization of Makaradhwaja prepared by Astasamskarita Parada


1 Lecturer, Dept. of Rasashastra and Bhaishajya Kalpana, I.P.G.T.& R.A., Gujarat Ayurved University, Jamnagar-361008, India
2 Reader & Head, dept. of Rasashastra and Bhaishajya Kalpana, I.P.G.T.& R.A., Gujarat Ayurved University, Jamnagar-361008., India

Correspondence Address:
B J Patgiri
Lecturer, Dept. of Rasashastra and Bhaishajya Kalpana, I.P.G.T.& R.A., Gujarat Ayurved University, Jamnagar-361008
India
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Source of Support: None, Conflict of Interest: None


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Makaradhwaja is one of the most popular Kupipakwa preparations of Ayurvedic medicine. It is prepared by shuddha Swarna (Gold), Astasamskarita Parada (Mercury) and shuddha Gandhaka (Sulphur) in the ratio of 1:8:16 as ingredients. The present study was under taken to standardize the pharmaceutical procedure of Makaradhwaja prepared by Astasamskarita Parada on the level of temperature pattern and duration through Electric muffle furnace to obtain maximum yield. Total 28.32 % loss of Parada was observed during preparation of Astasamskara. The test sample of Makaradhwaja was prepared in three batches to maintain the Standard procedure by using specially designed vertical electric muffle furnace. 252.84g, 252.84g and 246.97g of Kajjali was used to produce the yield of Makaradhwaja 89.35g, 85.12g and 80.24g of respectively consuming time duration of 18.40 hrs, 18.20 hrs and 18.35 hrs respectively till switching off of the heating device. The average time duration required for complete process i.e. starting of heating to self-cooling stage [50΀ C] was about 37 to 39 hours.


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