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   2007| January-March  | Volume 28 | Issue 1  
    Online since September 1, 2010

 
 
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RESEARCH ARTICLES
An Ayurvedic Management of Vulvovaginitis during Pregnancy
Neelam , Deepshikha Joshi, Neeraj Kumar
January-March 2007, 28(1):5-10
Vulvovaginitis is more common problem of pregnant women that challenges the gynaecologist. It is an inflammatory condition of the vulva and vagina and characterized by vaginal discharge, pain & itching in external genital organs. Various pathogens are responsible for this condition such as bacteria, parasite, mycotic and virus. Any infection in birth canal may cause premature rupture of membrane and preterm labour resulting in pregnancy loss. Diagnosis is made on the basis of clinical features and presence of pathogens in wet slide study and vaginal swab culture. Treatment depends upon the causative organisms with systemic or local drugs. Aim of study was to see the efficacy of Panchavalkala ointment in vulvovaginitis during pregnancy. Total 50 cases were selected and divided into 2 groups according to the different treatment. Patients were called weekly interval to observe any change and findings were recorded. Results were assessed on the basis of symptomatic relief and absence of pathogens in wet slide study and vaginal swab culture. Panchavalkala ointment is more effective against Trichomonas Vaginalis & E. Faecalis in comparison to Triclovate ointment.
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A comparative Pharmaceutico - Pharmaco - Clinical Study of Lauha Bhasma and Mandura Bhasma w. s. r. to its Panduhara Effect
PK Sarkar, PK Prajapati, AK Choudhary, S De, B Ravishankar
January-March 2007, 28(1):11-16
Lauha Bhasma and Mandura Bhasma, the most frequently used Ayurvedic preparation of metallic iron, were prepared by classical as well as mechanical methods, to lay down standard operating procedure (SOP) for preparing these Bhasmas. Both the Bhasmas were chemically analyzed and pharmacologically and clinically investigated in iron deficiency anaemia. Analytical study of Lauha Bhasma and Mandura Bhasma revealed the presence of various proportions of important metals along with varied concentration of iron in these. The effect of both the Bhasmas in the management of Panduroga i.e iron deficiency anaemia in animal model as well as human were found to be statistically significant in comparison to the reference standard drug dried ferrous sulphate treatment group. Mandura Bhasma was found to be a better haematinic than Lauha Bhasma in comparison to reference standard drug.
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A Clinical Trial of the Efficacy of Kalashaka Yoga in Medo Vruddhi (Hypercholesterolemia)
E.R.H.S.S. Ediriweera, KM Ranbanda, J Wellihinda
January-March 2007, 28(1):1-4
High prevalence of Hypercholesterolemia in the society is mainly due to lack of exercises and high intake of fatty foods. It can be correlated with Medo Vruddhi, a disease described in Ayurveda. This clinical study deals with the management of Medo Vruddhi (Hypercholesterolemia) using Kalashaka Yoga. This is widely used by the eminent Sri Lankan Traditional Physician Family 'Ranbanda'. Kalashaka Yoga is prepared using 20Kg of bulb of Allium sativum, 20Kg of leaves of Murraya koenigii, 5Kg of seeds of Piper nigrum, 10Kg of leaves of Aporosa lindleyana, 10Kg of leaves of Olax zeylanica. These ingredients are dried, ground with Bees' honey and made into pills weighing 125mg. Hundred Medo Vruddhi (Hypercholesterolemia) patients were selected and randomly divided into two groups. First group was treated with two pills of 125gm of Kalashaka Yoga twice a day for twelve weeks. Second group was treated with placebo, prepared by roasted bran of rice ground with warm water and made into 125gm pills, given two pills twice a day for twelve weeks. The response to treatment was recorded and therapeutic effect was evaluated through symptomatic relief of the patients and lipid profile. Significant symptomatic relief in xanthomatosis, heaviness in the body, softness in the body, dyspnoea even on slight exertion, excessive hunger, snoring, less enthusiasm and statistically significant marked reduction in serum cholesterol, triglycerides, low density lipoprotein was observed in the group treated with Kalashaka Yoga.
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A Pharmacological Study on Hypnotic Activity of Mamsyadi Ghrita
Anil Kumar Singh, B Ravishankar, HM Chandola
January-March 2007, 28(1):17-22
This study has been carried out to find out whether pharmacological basis exist for the use of Mamsyadi Ghrita- sleep promoting formulation consisting of Nardostachys Jatamansi, Convolvulus pluricaulis, Withania somnifera and Valeriana jatamansi in equal ratio. Sleep promoting drugs are supposed to posses CNS depression activity and majority of such depressants normally possess anti-anxiety activity. Based on this premise the test ghrita has been studied on various experimental models such as Gross behaviour test, Open field behaviour test and Plus maze test etc. On Swiss albino mice. Gross Behaviour Study, Mamsyadi Ghrita showed mild hypoactivity. In Elevated Plus Maze Test, the drug produced significant decrease in the duration spent in open tunnel indicating pro-anxiety activity. In the Open Field Apparatus Study, Mamsyadi Ghrita showed no effect on number of squares crossed. On Hypnotic Potentiation Test, the present study showed nonsignificant but moderate prolongation.
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