AYU (An International Quarterly Journal of Research in Ayurveda)

PHARMACOLOGICAL STUDY
Year
: 2016  |  Volume : 37  |  Issue : 1  |  Page : 67--70

Rasayana effect of Guduchi Churna on the life span of Drosophila melanogaster


Pankaj Pathak1, Mahesh Vyas2, Hitesh Vyas2, Mukesh Naria3 
1 Department of Basic Principles, JSS Ayurveda Medical College, Mysore, Karnataka, India
2 Department of Basic Principles, Institute for Postgraduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India
3 Department of Pharmacology Laboratory, Institute for Postgraduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India

Correspondence Address:
Pankaj Pathak
Department of Basic Principles, JSS Ayurveda Medical College, Mysore - 570 028, Karnataka
India

Introduction: The Drosophila melanogaster is one of the most extensively studied animal models for understanding the process of aging and longevity. This fly is being used for genetic studies since almost a century. Guduchi (Tinospora cordifolia [Wild.] Miers.) is an Ayurvedic drug used as Rasayana (rejuvenation) due to its antiaging effect. Aim: To explore the potential of Guduchi Churna (powder of T. cordifolia) on the life span of D. melanogaster using adult feeding method. Materials and Methods: For experimental setups, the regular food media were mixed with Guduchi Churna in different concentrations (0.25 g/100 ml, 0.50 g/100 ml, and 0.70 g/100 ml). Flies were exposed to these concentrations for 30 days. Results: Increase in the lifespan was observed in both parent and F-1 generation. Applying of ANOVA revealed significant difference between control and drug groups. The longevity effect, in the drug group was seen even on F-1 generation. Conclusion: Guduchi Churna enhances the life span of D. melanogaster in both parent and F-1 generation.


How to cite this article:
Pathak P, Vyas M, Vyas H, Naria M. Rasayana effect of Guduchi Churna on the life span of Drosophila melanogaster.AYU 2016;37:67-70


How to cite this URL:
Pathak P, Vyas M, Vyas H, Naria M. Rasayana effect of Guduchi Churna on the life span of Drosophila melanogaster. AYU [serial online] 2016 [cited 2020 Apr 5 ];37:67-70
Available from: http://www.ayujournal.org/article.asp?issn=0974-8520;year=2016;volume=37;issue=1;spage=67;epage=70;aulast=Pathak;type=0