Login   |  Users Online: 1260 Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Search Article 
  
Advanced search 
   Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | Subscribe | Contacts


 
  Table of Contents  
LETTER TO EDITOR
Year : 2018  |  Volume : 39  |  Issue : 4  |  Page : 256  

Kaphaja, Kapha-Pittaja Prakriti, methylenetetrahydrofolate reductase C677T allele and type 2 diabetes


1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Department of Community Medicine, Dr. DY Patil University, Pune, Maharashtra, India

Date of Web Publication5-Jul-2019

Correspondence Address:
Dr. Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok
Thailand
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ayu.AYU_44_19

Rights and Permissions

How to cite this article:
Joob B, Wiwanitkit V. Kaphaja, Kapha-Pittaja Prakriti, methylenetetrahydrofolate reductase C677T allele and type 2 diabetes. AYU 2018;39:256

How to cite this URL:
Joob B, Wiwanitkit V. Kaphaja, Kapha-Pittaja Prakriti, methylenetetrahydrofolate reductase C677T allele and type 2 diabetes. AYU [serial online] 2018 [cited 2019 Sep 22];39:256. Available from: http://www.ayujournal.org/text.asp?2018/39/4/256/262158



Dear Editor,

We read the publication on “Association of Kaphaja and Kapha-Pittaja Prakriti and methylenetetrahydrofolate reductase C677T allele with type 2 diabetes” with a great interest.[1] Gupta et al. noted that “The present study gives a strong clue for the association of Prakriti (body constitutional) and clinical phenotype.[1]” Indeed, this finding is interesting and can confirm that the classical knowledge is still presently merit for explanation of the common metabolic disease. However, there are some points that should be noted. The diabetic patient might have other concurrent problems. Metabolic syndrome (diabetes mellitus, dyslipidemia, hypertension and obesity) is very common worldwide. The other common diseases in the group of metabolic syndrome might affect the relationship between Kaphaja and Kapha-Pittaja Prakriti and methylenetetrahydrofolate reductase C677T allele. Furthermore, aging is another important factor that is related to Kaphaja and Kapha-Pittaja Prakriti. The pattern of phenotype might be different at different ages.[2] In addition, there are also other common genetic factors that are related to diabetes mellitus.[3] The association between Kaphaja and Kapha-Pittaja Prakriti and clinical phenotype might be affected by those genetic factors. Finally, it should be noted that a holistic concern bio-psycho-social-spiritual dimension or Vataja, Pittaja and Kaphaja dimension should be mentioned if we would like to discuss on a phenotype of a medical problem. For diabetes pathophysiology, the recent reports showed that Vata has more influence than Pitta and Kapha on insult-related phenotype in diabetic patients.[4]

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
   References Top

1.
Gupta A, Ali A, Tewari P, Agrawal NK, Patel R, Byadgi PS, et al. Association of kaphaja and Kapha-pittaja prakriti and methylenetetrahydrofolate reductase C677T allele with type 2 diabetes. Ayu 2018;39:146-50.  Back to cited text no. 1
[PUBMED]  [Full text]  
2.
Purvya MC, Meena MS. A review on role of prakriti in aging. Ayu 2011;32:20-4.  Back to cited text no. 2
[PUBMED]  [Full text]  
3.
Cohen D, Haguenauer-Cohen O, Hors J, Deschamps I, Dausset J. Molecular genetics of juvenile diabetes. Journ Annu Diabetol Hotel Dieu 1985;21:157-69.  Back to cited text no. 3
    
4.
Chandola HM, Tripathi SN, Udupa KN. Variations in the progenesis of maturity onset diabetes according to body constitution. Anc Sci Life 1994;13:293-301.  Back to cited text no. 4
    




 

Top
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
    References

 Article Access Statistics
    Viewed168    
    Printed2    
    Emailed0    
    PDF Downloaded54    
    Comments [Add]    

Recommend this journal