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PHARMACEUTICAL STUDY
Year : 2018  |  Volume : 39  |  Issue : 1  |  Page : 34-39

Establishment of quality function deployment with special reference to good manufacturing practice of Chandraprabha Vati


Department of Pharmaceutical Chemistry, IPGT and RA, Gujarat Ayurved University, Jamnagar, Gujarat, India

Correspondence Address:
Mr. Abhay Jayprakash Gandhi
Department of Pharmaceutical Chemistry, IPGT and RA, Gujarat Ayurved University, Jamnagar - 361 008, Gujarat
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ayu.AYU_44_18

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Context: Quality function deployment (QFD) is a powerful tool for the translation of vague, imprecise customer requirements into clear, measurable technical requirements. Aims: The objective of this article is twofold: (a) to propose a platform conceptual model for Chandraprabha Vati and (b) to present 10-step procedure to build QFD matrix. Materials and Methods: The method deals with, first, preparing two conceptual models for Chandraprabha Vati for the sake of manufacturing unit. The survey study was carried out for two products for the selection of customer requirement. Then, with the help of survey study QFD's house of quality matrix was prepared which contained two products, i.e., classical product prepared by pharmacy of university and marketed product. High performance thin layer chromatography study was also carried out. Statistical Analysis Used: Principal component analysis (PCA) was applied to the data using unscrambler software. Results: The results of QFD chart and PCA analysis were obtained from the two surveys. The first survey reveals that if proper care is taken during preparation on hardness and capping of Vati, then product goes toward zero defects. The second survey reveals that if proper care is taken during preparation on hardness, capping and sticking, then physically Vati goes toward zero defects. Conclusions: The 10-step procedure facilitates the process of reasoning and reduces the time spent for manufacturing with zero defect in product.


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