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CASE STUDY
Year : 2015  |  Volume : 36  |  Issue : 2  |  Page : 174-176

Adverse reaction of Parasika Yavani (Hyoscyamus niger Linn): Two case study reports


1 One World Ayurveda, Bali, Republic of Indonesia
2 Chair of Ayurveda, Universitas Hindu Indonesia (UNHI), Denpasar, Bali, Republic of Indonesia
3 Department of Basic Principles, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University Jamnagar, Gujarat, India

Correspondence Address:
Dr. K Aparna
Consulting Physician, Purnayoo Arogya Nikethanam, Ayurveda and Yoga Research Centre, Meenangadi - 673 591, Kerala, India

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-8520.175550

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Adverse drug reaction (ADR) is an unpleasant reaction related to the use of medicine at its therapeutic dose. Ayurveda is well aware of such adverse reactions. Parasika Yavani (Hyoscyamus niger Linn.) is an Ayurvedic drug effectively used in many psychological disorders, if not used judiciously it causes adverse reactions. In present study two cases of ADR on the usage of Parasika Yavani are reported. Churna in capsule form given in different dosage forms (500 mg once a day, 250 mg twice a day, 250 mg once a day) in Chittodwega (generalised anxiety disorder). 500mg capsule was given to many patients in the study, but no adverse reactions were noticed except in above given two cases. So, in these two cases, the dose was tapered down to 250 mg twice a day, and then to 250 mg once a day to avert the adverse reactions and to fix the therapeutic dose in such individuals (250 mg once a day). On analysis, these two individuals were found to be of Pitta Prakriti. Parasika Yavani is found to increase Pitta and triggers the establishment of ADRs. So, while administering therapeutic dosage, a physician should be vigilant. In the current study, it is observed that 500 mg of Parasika Yavani powder in Pitta Prakriti individuals triggered ADRs while 250 mg once a day was safe. It was also observed that Kapha and Vata Prakriti, patients did not develop any adverse reactions.


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