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CLINICAL RESEARCH
Year : 2011  |  Volume : 32  |  Issue : 4  |  Page : 532-535  

Effect of Ayurvedic herbs on control of plaque and gingivitis: A randomized controlled trial


1 Senior Research Associate, INYS Medical Research Society, Bangalore, India
2 Principal, KLE University's BMK Ayurveda Mahavidyalaya, Belgaum, Karnataka, India
3 PG Scholar, KLE University's V.K. Institute of Dental Sciences, Belgaum, Karnataka, India
4 Lecturer, Department of Shalakya Tantra, KLE University's BMK Ayurveda Mahavidyalaya, Belgaum, Karnataka, India

Date of Web Publication14-May-2012

Correspondence Address:
B S Prasad
Principal, KLE University's, BMK Ayurved Mahavidyalaya, Belgaum, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-8520.96128

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   Abstract 

Ayurveda had mentioned various procedures for maintaining oral hygiene. These include procedures like gandusha, kavala, dantadhavana, and jivha lekhana (cleaning tongue). Various plants have been mentioned in Ayurveda for dantakashta. Various Ayurvedic dental formulations are available in market in the form of powders, paste, etc. Present study was conducted for evaluating the effect of one of such Ayurvedic toothpowder named UDM, in controlling plaque and reducing gum inflammation in patients of moderate gingivitis. Scaling, root planning, and polishing were done for all the patients participating in the study. Oral hygiene instructions were given that included brushing twice/day with assigned tooth powder using BASS method for tooth brushing and also massage over gum tissue with finger. All the patients were recalled after 15 days. Scores of plaque index and gingival index was recorded on day 1 and day 15 of treatment. Total of 15 patients were recruited in each group. The mean reduction in gingival index was 1.15 (P<0.05) and 1.26 (P<0.05) in positive control and UDM treatment groups, respectively. However, the mean reduction in plaque indices were found to be 2.03 (P<0.05) and 2.16 (P<0.05) in positive control and UDM groups, respectively. No significant difference was seen in both the parameters between the two groups.

Keywords: Ayurveda, gingivitis, oral hygiene, periodontal diseases


How to cite this article:
Kadam A, Prasad B S, Bagadia D, Hiremath V R. Effect of Ayurvedic herbs on control of plaque and gingivitis: A randomized controlled trial. AYU 2011;32:532-5

How to cite this URL:
Kadam A, Prasad B S, Bagadia D, Hiremath V R. Effect of Ayurvedic herbs on control of plaque and gingivitis: A randomized controlled trial. AYU [serial online] 2011 [cited 2019 Nov 21];32:532-5. Available from: http://www.ayujournal.org/text.asp?2011/32/4/532/96128


   Introduction Top


Periodontal diseases are universal and have been known to affect mankind since the beginning of the recorded history. This fact has been proved by many documentary and paleopathological studies. They also form a major global public problem. There is ample evidence to implicate dental plaque as the primary etiological agent responsible for periodontal diseases. It has been shown that early stages of gingivitis can be reversed by meticulous plaque removal through oral hygiene procedures. Prevention and control of dental plaque by daily rinsing with antibacterial agents have seemed to be attainable ideals since Le and Schiott [1] demonstrated the clinical effects of chlorhexidine rinses in human subjects.

The prevention and treatment of periodontal diseases involve control of plaque deposits mainly by mechanical plaque control methods such as scaling and root planning to achieve ideal plaque control. However, various homecare methods are developed such as tooth brushes, interdental aids, therapeutic dentifrices, etc.

Various studies have been conducted with various agents to study their effect in plaque control. Konig [2] demonstrated that a 0.1% SnF 2 solution, applied daily to rat molars, inhibited plaque and led to substantial caries reduction. This study first demonstrated the advantage of stannous fluoride rinses for the inhibition of plaque; Shern et al. substantiated those earlier findings. In one study [3] the plaque-inhibiting effect of an SnF 2 solution was equivalent to that of chlorhexidine, when each was used twice daily. Tinanoff et al. [4] showed almost total inhibition of plaque and bacteria with a twice-daily rinse of 0.1% SnF 2 . In a separate study, Shern et al. demonstrated the plaque-inhibiting effect of fluoride rinse. [5] No agent utilized to date has been entirely satisfactory. [6]

Ayurveda is an ancient system of medicine and is a rich reservoir of resources even for the dental sciences. Ayurveda has mentioned various procedures for maintaining oral hygiene. These include procedures like gandusha, kavala, dantadhavana, and jivha lekhana.

In Gandusha, water processed with various medicinal herbs is held in mouth for certain duration. In kavala, water is moved in mouth. However, danta dhavana is cleaning of teeth. Danta dhavana is to be done with stem of certain plants (called as dantakashta) like vata, asana, arka, khadira, karavira, amarga, etc. It is told that the length of the dantakashta should be of 12 anguli pramana (length equal to that of width of 12 figures) and the thickness should be about the circumference of little finger. It should possess kashaya (Astringent), tikta (bitter), and katu (pungent) rasas. These drugs have properties like kriminashaka/jantughana (antiseptic), vranaropaka (heals wounds), and raktashodhaka (blood purifier). The herbs used in UDM tooth powder are predominant in these rasas and gunas; hence, these can be used in treatment of gingivitis

Interest towards the use of herbal-based products is on the rise and it is true even for dentistry. There are various herbs which are proved to be having antiseptic effect. Even today, in India, many herbs are used for cleaning teeth. If herbs are found to be effective in plaque control, it will serve to be of great importance in the maintenance of oral health in treating the periodontal problems in a more economical and safer way.

Today, hundreds of dentifrices are available in the market, but it is necessary to verify the efficacy of these dentifrices by clinical trials instead of simply assuming that the product is efficient based on laboratory studies or advertisement made by manufacturers.

The present study was conducted on one of such proprietary herbal tooth powders named "UDM," manufactured by KLE Ayurveda pharmacy, Belgaum.

The formulation composition is placed at [Table 1].
Table 1: Composition of UDM tooth powder per 10 g

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The study was conducted to evaluate the efficacy of a UDM Ayurvedic tooth powder in the control of plaque and to check the efficacy of a UDM Ayurvedic tooth powder in the reduction of gingival inflammation in patient with moderate gingivitis. [7]


   Materials and Methods Top


Study was conducted at KLE society's V. K. Institute of Dental Sciences, Belgaum. Thirty patients reporting at the outpatient department of Periodontics and diagnosed clinically as case of moderate gingivitis with probing depth of ≤3 mm and a minimum of 15 teeth were included in the study. Moderate gingivitis was defined as extension of inflammation to form a continuous band along the marginal gingivae of more than three regions or teeth. These subjects were randomly assigned to one of the two study groups, after an informed consent process. The two groups were test group (UDM tooth powder) and positive control group (well-established brand tooth powder). Study procedure was explained to patients participating in the study. Each of the treatment groups was consisting 15 subjects.

Patients with presence of advanced periodontal disease, use of orthodontic appliances, use of antibiotics in previous 3 months, continuous use of mouth rinses in previous 3 months, history of allergy to dentifrices, or history of any uncontrolled systemic diseases were excluded.

Scaling, root planning, and polishing were done for all the patients participating in the study. Oral hygiene instructions were also given to each subject, which included brushing twice a day with assigned tooth powder using BASS method for tooth brushing and also massage over gum tissue with finger. All the patients were reassessed after 15 days. Scores of plaque index and gingival index was recorded on day 1 and day 15 of treatment.

The examination was done by the investigator who was assisted by the recorder well trained with the procedure. Oral inspection was done using a mouth mirror and William's probe, in adequate illumination. Efficacy parameters were assessed by Plaque Index (Quigley and Hein, 1962 modified by Turesky-Gilmore-Glickman, 1970) and Gingival Index (Loe and Silness 1963).

Plaque was assessed on the labial, buccal, and lingual surfaces of all the teeth after using two-tone disclosing agent (Alpha Plac® ). Gingival index was recorded on all surfaces of all the teeth and score was given for each surface from 0 to 3 according to the scoring criteria. William's probe was used to assess the bleeding potential of the tissue.

Statistical significance of mean changes between day 1 and day 15 in the above parameters were assessed using paired t tests. Difference in scores between the two groups was analyzed using unpaired t tests. Statistical analyses were performed with SPSS software for Windows (Statistical Product and Service Solutions, version 15.0, SSPS Inc, Chicago, IL, USA).


   Results Top


Of the 30 patients enrolled in the study, all completed the entire study duration of 15 days.

There was a significant reduction between scores of gingival index on day 1 and day 15 in both the groups. No significant difference was seen in scores between the two groups at the end of treatment period [Table 2], [Figure 1].
Figure 1: Changes in gingival index

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Table 2: Scores of gingival index on the starting day of treatment and that on day 15 in positive control group

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Table 3: Scores of plaque index on the starting day of treatment and that on day 15 in positive control group

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Significant reduction was also observed between scores of plaque index on day 1 and day 15 in both the groups. There was no significant difference between the two groups at the end of treatment period [Table 3],[Figure 2].
Figure 2: Change in score of plaque index in UDM and positive control group

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   Discussion Top


Plaque and gingivitis are important diseases of oral cavity and comprises a major part of patients visiting dentists. Various herbs are mentioned in Ayurvedic classics, which can be used for plaque control and treatment of gingivitis.

The study compared herbal tooth powder UDM with a standard control. Both the tooth powders were found to be useful in effectively reducing the scores of plaque index and gingival index after a treatment period of 15 days. The difference in pre and post scores of both the tooth powders was found to be statistically significant at 5% level of significance.

By comparing the change score between the two groups, it can be said that the difference in score of UDM group was slightly more than that in positive control group, but the difference between the two groups was not statistically significant (P>0.05) and thus superiority cannot be claimed. However, it can be said that UDM was as effective as that of positive control group in reducing score of plaque index and gingival index.

The strength of the study was its randomized controlled design. The drawback of the study was that it was done in relative small sample size and thus it was not powered to show a statistically significant difference between the two groups. Another drawback of the study was the open-labeled design. Despite the drawbacks, this study demonstrated the potential role of Ayurvedic herbs in management of periodontal diseases. More studies can be carried out in larger sample size to further evaluate these results.

Further studies are also required to determine how long the plaque-inhibiting effect of such herbal formulation lasts and what should be the optimal frequency of rinsing. Since herbal formulations act by synergy, it may not be possible to interpret the action of each individual ingredient based on findings of present study but various such experimentations can be carried out, which will help further to determine the therapeutic effect of each ingredient. Answers to these questions could lead to the development of evidence based plaque-and-caries-control regimens by the use of Ayurvedic herbs.


   Conclusion Top


The following conclusions can be drawn from the present study:

  • Both UDM toothpowder and standard control treatment group shows statistically significant reduction in scores of gingival index and plaque.
  • Both the groups showed a similar effect in treating gingivitis.
  • A poly herbal combination of herbs mentioned in Ayurveda for oral hygiene has a potential for management of gingivitis.


 
   References Top

1.Le H, Schiott CR. The Effect of Suppression of the Oral Microflora Upon the Development of Dental Plaque and Gingivitis. In: Dental Plaque, W.D. McHugh, editors. Edinburgh: E.S. Livingston; 1969.  Back to cited text no. 1
    
2.Konig KG. Dental Caries and Plaque Accumulation in Rats Treated with Stannous Fluoride and Penicillin, Helv Odont Acta 1959;3:39-44.  Back to cited text no. 2
    
3.Svatun B, Gjermo P, Eriksen H, Rolla G. A comparison of the Plaque Inhibiting Activity of Stannous Fluoride and Chlorhexidine, Acta Odontol Scand 1977;35:247-50.  Back to cited text no. 3
    
4.Tinanoff N, Brady JM, Gross A. The Effect of NaF and SnF2 Mouthrinses on Bacterial Colonization of Tooth Enamel: TEM and SEM Studies. Caries Res 1976;10:415426.  Back to cited text no. 4
    
5.Shern RJ, Couet DM, Kingman A. Effects of Various Fluoride Rinses on Dental Plaque in Rats, J Dent Res 1978;57: A114.  Back to cited text no. 5
    
6.Leverett DH, Mchugh WD, Jensen OE. Effect of Daily Rinsing with Stannous Fluoride On Plaque and Gingivitis: Final Report. J Dent Res 1984;63:1083-6.  Back to cited text no. 6
[PUBMED]  [FULLTEXT]  
7.Davies GN. Dental Conditions Among the Polynesians of Pukapuka (Danger Island): II. The Prevalence of Periodontal Disease. J Dent Res 1956;35:734-41.  Back to cited text no. 7
[PUBMED]  [FULLTEXT]  


    Figures

  [Figure 1], [Figure 2]
 
 
    Tables

  [Table 1], [Table 2], [Table 3]


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