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PHARMACEUTICAL CHEMISTRY
Year : 2010  |  Volume : 31  |  Issue : 3  |  Page : 382-386

Impact of Bhavana Samskara on physico-chemical parameters with special reference to Gandhaka Rasayana prepared by different media and methods


1 Department of Rasa shastra, Govt. Ayurvedic College, Rampur Chauraha, Mujaffarnagar (U.P.), India
2 Department of Rasa shastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India
3 Pharmaceutical laboratory, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India
4 Pharmacological laboratory, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India

Correspondence Address:
P K Prajapati
Professor & Head, Department of Rasashastra and Bhaishajya Kalpana including Drug Research, I.P.G.T & R.A., Gujarat Ayurved University, Jamnagar, Gujarat
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-8520.77155

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Gandhaka Rasayana is frequently used in the management of different skin disorders (Kushtha). It is a herbo-mineral preparation prepared by Shuddha Gandhaka Bhavit with 11 herbal drugs in a serial manner for eight times each. Therefore, it was used as a model drug and four samples were prepared by adopting different methods and media. The physicochemical parameters were evaluated. The effect of increasing the number of Bhavana (lavigation) on particle size of the drug was examined. Similarly, an attempt was also made to differntiate the structure (surface anatomy) of the drug with Bhavana and without Bhavana by using a very sophisticated x-ray photo electron spectrometer (XPS) study. Overall, a remarkable difference was observed in the samples with Bhavana and without Bhavana.


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