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RESEARCH ARTICLE
Year : 2009  |  Volume : 30  |  Issue : 2  |  Page : 205-210

An Experimental Study on Hypolipidemic effect of some selected Ruksha Guna drugs


1 Ph.D. (Ayu.), Dept. of Basic Principles, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India
2 Professor & H.O.D - Basic Principles, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India
3 Head -Pharmacology Laboratory, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India
4 Senior Research Fellow (CCRAS) - Pharmacology Lab., Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India

Correspondence Address:
Sangram Mishra
Ph.D. (Ayu.), Dept. of Basic Principles, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar
India
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Source of Support: None, Conflict of Interest: None


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Ayurveda as well as Philosophies accepted the Guna as the basic entity of the Srishti. Gunas can be classified under various categories like Adhyatmika Guna, Gurvadi Guna, Paradi Guna, Vishistha Guna. For the treatment purpose Gurvadi Gunas are widely used. Among them the Snigdha Guna and Ruksha Guna are widely used in the Samhitas. This study has been carried out to establish the Ruksha property drugs on animals as a hypolipidemic effect on induced hyperlipidemia animals. The drugs selected were having Ruksha property by Rasa panchaka. The drugs were Vacha (Acorus calamus Linn), Kushtha (Saussurea lappa C.B. Clarke), Haridra (Curcuma longa Linn), Daruharidra (Berberis aristata DC), Chitraka (Plumbago zeylanica), Karanja (Pongamia pinnata Pierre). All the drugs are having Lekhana property and Srotosodhaka karma due to Ruksha property. Based on this promise the test drug (Ruksha Guna) had been studied on various experimental models such as body weight, weight of liver, heart and kidney, food intake and faecal out put, water intake, total faecal fat content etc. The selected drugs are the representative of highest magnitude of Ruksha property which are able to influence Dipana and Pachana property and the test drug was administered with the simultaneous administration of hyperlipidemia inducing diet, but the biochemical values are found under control.


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