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RESEARCH ARTICLE
Year : 2007  |  Volume : 28  |  Issue : 2  |  Page : 38-46

A Comparative Pharmaceutical and Analytical Study of Shirisharishta Prepared by Bark, Sapwood and Heartwood of Albizia Lebbeck Benth


1 M.D. (Ayu.) Scholar, Dept. of R.S. & B.K., Institute for Post Graduate Teaching & Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India
2 Reader & Head, Dept. of R.S. & B. K., Institute for Post Graduate Teaching & Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India
3 Lecturer, Dept. of R.S. & B. K, Institute for Post Graduate Teaching & Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India
4 Head, Pharmacology Lab., Institute for Post Graduate Teaching & Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India
5 Scientists, Indian Institute of Integrative Medicine [Formerly RRL], Jammu, India

Correspondence Address:
Mundeep Jaiswal
M.D. (Ayu.) Scholar, Dept. of R.S. & B.K., Institute for Post Graduate Teaching & Research in Ayurveda, Gujarat Ayurved University, Jamnagar
India
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Source of Support: None, Conflict of Interest: None


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Three batches of Shirisharishta were prepared by using Twak (bark), Kastha (sapwood) and Sara (heartwood) of Shirisha, following classical method and analyzed. The pharmaceutical analysis revealed that the Shirisharishta prepared by Sara (heartwood) showed earlier onset and completion, better fermentation, 17 % more yielding, pleasant aroma and more alcoholic than others. The average pH was observed 4.74, 4.56 and 4.45 respectively in Shirisharishta prepared by bark, sapwood and heartwood and alcohol percentage was observed 3.93, 3.64 and 4.96 respectively. The HPTLC analysis was carried out to develop a fingerprint profile for the formulation. HPLC analysis showed the presence of epigallocatechin gallate, piperine and curcumin in all the three samples but maximum of their presence of percentage in heartwood preparation of Shirisharishta.


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