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RESEARCH ARTICLE
Year : 2006  |  Volume : 27  |  Issue : 2  |  Page : 26-29

Effect of Azadirachta indica A. Juss. on Falciparum Malaria cases in Car-Nicobar


Clinical Research Unit, Safdarjung Hospital, Central Council for Research in Ayurveda & Siddha, New Delhi; Arignar Anna Govt. Hospital of Indian Medicine, Chennai-600 160; Ayurvedic Hospital, T. Nagar, Chennai - 600 170, India

Correspondence Address:
Raakhee Mehra
Clinical Research Unit, Safdarjung Hospital, Central Council for Research in Ayurveda & Siddha, New Delhi; Arignar Anna Govt. Hospital of Indian Medicine, Chennai-600 160; Ayurvedic Hospital, T. Nagar, Chennai - 600 170
India
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Source of Support: None, Conflict of Interest: None


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Thirty patients of uncomplicated Plasmodium falciparum malaria completed a clinical trial of Azadirachta indica A Juss conducted in malaria endermic Tamalu & Orong villages of tribal pockets in Car-Nicobar District of Andaman & Nicobar Islands. The decoction of bark of Azadirachta indica. A. Juss made out of 50 gm crude powder was given thrice a day for four consecutive days. The cure rate was 100 percent with mean fever & parasite clearance time of 42.4 ΁ 17.5 & 37.6 ΁ 13.6 h respectively. Recrudescence/reinfection rate was 01%. Palpable spleen on day 0 became non-palpable within 21 days. Following the treatment, percentage of h aemoglobin varied marginally with no remarkable change in total & differential leucocyte count. Azadirachta indica A. Juss besides being a potent & fast acting schizontocidal drug, also reported gametocytocidal action on P. falciparum. AYU will supply 10 reprints free of charge to the Principal author whose paper is published, in case of multiple authors only the first author will be supplied the reprints.


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